| Title |
Surge of neurophysiological coherence and connectivity in the dying brain
|
|---|---|
| Published in |
Proceedings of the National Academy of Sciences of the United States of America, August 2013
|
| DOI | 10.1073/pnas.1308285110 |
| Pubmed ID | |
| Authors |
Jimo Borjigin, UnCheol Lee, Tiecheng Liu, Dinesh Pal, Sean Huff, Daniel Klarr, Jennifer Sloboda, Jason Hernandez, Michael M. Wang, George A. Mashour |
| Abstract |
The brain is assumed to be hypoactive during cardiac arrest. However, the neurophysiological state of the brain immediately following cardiac arrest has not been systematically investigated. In this study, we performed continuous electroencephalography in rats undergoing experimental cardiac arrest and analyzed changes in power density, coherence, directed connectivity, and cross-frequency coupling. We identified a transient surge of synchronous gamma oscillations that occurred within the first 30 s after cardiac arrest and preceded isoelectric electroencephalogram. Gamma oscillations during cardiac arrest were global and highly coherent; moreover, this frequency band exhibited a striking increase in anterior-posterior-directed connectivity and tight phase-coupling to both theta and alpha waves. High-frequency neurophysiological activity in the near-death state exceeded levels found during the conscious waking state. These data demonstrate that the mammalian brain can, albeit paradoxically, generate neural correlates of heightened conscious processing at near-death. |
X Demographics
The data shown below were collected from the profiles of 215 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 35 | 16% |
| Japan | 24 | 11% |
| United Kingdom | 9 | 4% |
| Argentina | 4 | 2% |
| Canada | 3 | 1% |
| Sweden | 3 | 1% |
| France | 3 | 1% |
| Australia | 2 | <1% |
| Ireland | 2 | <1% |
| Other | 24 | 11% |
| Unknown | 106 | 49% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 180 | 84% |
| Scientists | 24 | 11% |
| Science communicators (journalists, bloggers, editors) | 6 | 3% |
| Practitioners (doctors, other healthcare professionals) | 3 | 1% |
| Unknown | 2 | <1% |
Mendeley readers
The data shown below were compiled from readership statistics for 504 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 12 | 2% |
| Germany | 4 | <1% |
| Japan | 4 | <1% |
| United Kingdom | 4 | <1% |
| France | 3 | <1% |
| Netherlands | 3 | <1% |
| Cuba | 2 | <1% |
| Australia | 2 | <1% |
| Spain | 2 | <1% |
| Other | 11 | 2% |
| Unknown | 457 | 91% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 102 | 20% |
| Researcher | 85 | 17% |
| Student > Master | 57 | 11% |
| Student > Bachelor | 47 | 9% |
| Professor | 34 | 7% |
| Other | 108 | 21% |
| Unknown | 71 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 86 | 17% |
| Neuroscience | 77 | 15% |
| Psychology | 75 | 15% |
| Medicine and Dentistry | 68 | 13% |
| Engineering | 38 | 8% |
| Other | 71 | 14% |
| Unknown | 89 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1931. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2024.
All research outputs
#4,969
of 25,646,963 outputs
Outputs from Proceedings of the National Academy of Sciences of the United States of America
#166
of 103,514 outputs
Outputs of similar age
#13
of 209,955 outputs
Outputs of similar age from Proceedings of the National Academy of Sciences of the United States of America
#1
of 897 outputs
Altmetric has tracked 25,646,963 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 103,514 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 39.6. This one has done particularly well, scoring higher than 99% of its peers.
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We're also able to compare this research output to 897 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.